Preimplantation Genetic Diagnosis (PGD) or Screening (PGS) refers to a procedure whereby embryos attained through an IVF cycle are evaluated for genetic disorders prior to implantation. The purpose of this test is to help prevent certain diseases or disorders from being passed on to the child from the parent. In most cases, the female, male, or both partners have been genetically screened and identified to be carriers of potential problems.
The Ottawa Fertility Centre works with a reputable genetics lab in Detroit, Michigan called Cooper Genomics . Patients of the Ottawa Fertility Centre now have access to important genetic testing prior to an embryo transfer.
Who can benefit from PGD and PGS?
Any couple at risk for passing on a genetic disease or condition can benefit from pre-implantation genetic diagnosis and screening. Possible candidates include:
- Women aged 35 and over.
- Carriers of sex-linked genetic disorders.
- Carriers of single gene defects.
- Those with chromosomal disorders.
- Women experiencing recurring pregnancy loss associated with chromosomal concerns.
Benefits or advantages of PGD and PGS
- PGD enables couples to pursue biological children who might not have been able to do so otherwise.
- Performing PGD prior to implantation can reduce the need for amniocentesis later in pregnancy.
- PGD helps reduce the chance of conceiving a child with a genetic factor. However, it can not completely eliminate this risk. In some cases, further testing done during pregnancy is needed to ascertain if a genetic factor is still possible.
Information and Resources
Contact your physician at the Ottawa Fertility Centre for more information and to determine whether or not PGD/PGS is an appropriate treatment option for you.